LL-AF283 antibiotics, cyclic biphenyl peptides.
نویسندگان
چکیده
منابع مشابه
Novel pH-Sensitive Cyclic Peptides
A series of cyclic peptides containing a number of tryptophan (W) and glutamic acid (E) residues were synthesized and evaluated as pH-sensitive agents for targeting of acidic tissue and pH-dependent cytoplasmic delivery of molecules. Biophysical studies revealed the molecular mechanism of peptides action and localization within the lipid bilayer of the membrane at high and low pHs. The symmetri...
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Antimicrobial peptides (APs) have been described as evolutionary ancient weapons. Produced by a wide variety of organisms as part of a non-specific immune response, these peptides are involved in the direct destruction of various microorganisms. Several APs have been shown to have broad activity spectra against microorganisms such as Gram-positive and Gram-negative bacteria, enveloped viruses, ...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1991
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.44.674